{"id":1669,"date":"2014-02-08T10:07:30","date_gmt":"2014-02-08T10:07:30","guid":{"rendered":"http:\/\/sciences-unamur.be\/bio\/system-ecotox\/?page_id=1669"},"modified":"2025-09-21T14:55:51","modified_gmt":"2025-09-21T14:55:51","slug":"publications","status":"publish","type":"page","link":"https:\/\/sciences-unamur.be\/bio\/system-ecotox\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>Find PDF of major publications on the <a href=\"http:\/\/www.researchgate.net\/profile\/Frederic_Silvestre\/\" target=\"_blank\" rel=\"noopener noreferrer\">ResearchGate profile of Frederic Silvestre<\/a><\/p>\n<p><strong>2025<\/strong><\/p>\n<p>Epigenetic aging in a self-fertilizing vertebrate, the mangrove rivulus Kryptolebias marmoratus.<br \/>\nB\u00e9lik J. and Silvestre F. <strong>bioRxiv preprint<\/strong> (2025). https:\/\/doi.org\/10.1101\/2025.09.19.677260. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.09.19.677260v1\">Open Access<\/a><\/p>\n<p>Embryonic thermal environments drive plasticity in gene expression.<br \/>\nAnthony A. Snead, Corey R. Quackenbush, Shawn Trojahn, Anna L. McDonald, Luana S.F. Lins, Chris Cornelius, Paula E. Adams, Dengke Ma, Yuying Hsu, Eric Haag, Fr\u00e9d\u00e9ric Silvestre, Akira Kanamori, Ryan L. Earley &amp; Joanna L. Kelley. <strong>Fish Physiology and Biochemistry<\/strong>, 51 (2025). <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s10695-025-01522-x\">Open Access<\/a><\/p>\n<p>Water-borne cortisol levels show individuality and predict bold\/shy behaviors in the self-fertilizing fish Kryptolebias marmoratus.<br \/>\nMathiron G.E.A. and Silvestre F. <strong>Belgian Journal of Zoology<\/strong>, 155 (2025). <a href=\"https:\/\/belgianjournalofzoology.eu\/BJZ\/article\/view\/198\">Open Access<\/a><\/p>\n<p><strong>2024<\/strong><\/p>\n<p>Comparative study of the growth, stress status and reproductive capabilities of four wild-type zebrafish (Danio rerio) lines.<br \/>\nChevalier C., Denis C., Nedjar S.-A., Ledor\u00e9 Y., Silvestre F., Schaerlinger B. &amp; Milla S. <strong>Biological Research<\/strong>, 57 (2024). <a href=\"https:\/\/biolres.biomedcentral.com\/articles\/10.1186\/s40659-024-00549-3\">Open Access<\/a><\/p>\n<p><strong>2023<\/strong><\/p>\n<p>Environmental Epigenomes.<br \/>\nBambarendage P.U., Silvestre, F. <strong>Epigenomes<\/strong>, 7 (2023). <a href=\"https:\/\/www.scopus.com\/record\/display.uri?eid=2-s2.0-85172153488&amp;origin=resultslist&amp;sort=plf-f\">Open Access<\/a><\/p>\n<p>Tools for photomotor response assay standardization in ecotoxicological studies: Example of exposure to gentamicin in the freshwater planaria Schmidtea mediterranea.<br \/>\nMathiron, A., Rejo, L., Chapeau, F., Malgouyres Silvestre, F., Vignet, C. <strong>Environmental Toxicology and Pharmacology<\/strong>, 102 (2023), 104242. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1382668923001849?via%3Dihub\">Abstract<\/a><\/p>\n<p>Early-life exposure to permethrin affects phenotypic traits in both larval and adult mangrove rivulus Kryptolebias marmoratus.<br \/>\nMathiron, A, Gallego, G &amp; Silvestre, F. <strong>Aquatic Toxicology<\/strong>, 259 (2023). <a href=\"https:\/\/doi.org\/10.1016\/j.aquatox.2023.106543\">Abstract<\/a><\/p>\n<p>Early-life exposure to methylmercury induces reversible behavioral impairments and gene expression modifications in one isogenic lineage of mangrove rivulus fish Kryptolebias marmoratus.<br \/>\nChapelle, V, Lambert, J, Deom, T, Tessier, E, Amouroux, D &amp; Silvestre, F.\u00a0<strong>Aquatic Toxicology<\/strong>, 258 (2023). <a href=\"https:\/\/doi.org\/10.1016\/j.aquatox.2023.106474\">Abstract<\/a><\/p>\n<p><strong>2022<\/strong><\/p>\n<p>Population Epigenetics: The Extent of DNA Methylation Variation in Wild Animal Populations.<br \/>\nChapelle, V &amp; Silvestre, F.\u00a0<strong>Epigenomes<\/strong>, 6 (2022). <a href=\"https:\/\/doi.org\/10.3390\/epigenomes6040031\">doi.org\/10.3390\/epigenomes6040031.<\/a><\/p>\n<p>Genome-wide DNA methylation of the liver reveals delayed effects of early-life exposure to 17-\u03b1-ethinylestradiol in the self-fertilizing mangrove rivulus.<br \/>\nVoisin, A-S, Suarez Ulloa, V, Stockwell, PA, Chatterjee, A, Silvestre, F<strong>.<\/strong> <strong>Epigenetics<\/strong>, 17 (2022), 473-497. <a href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15592294.2021.1921337\">Abstract<\/a><\/p>\n<p><strong>2020<\/strong><\/p>\n<p>Behavior and gene expression in the brain of adult self-fertilizing mangrove rivulus fish (Kryptolebias marmoratus) after early life exposure to the neurotoxin \u03b2-N-methylamino-L-alanine (BMAA).<br \/>\nCarion, A, Markey, A, H\u00e9tru, J, Carpentier, C, Suarez-Ulloa, V, Deno\u00ebl, M, Earley, RL &amp; Silvestre, F. <strong>Neurotoxicology<\/strong>, 79 (2020), 110-121. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0161813X20300668?via%3Dihub\">Abstract<\/a><\/p>\n<p>Signaling pathways of oxidative stress in aquatic organisms exposed to xenobiotics.<br \/>\nSilvestre, F. <strong>J. Exp. Zool.<\/strong> Part A: Ecological and Integrative Physiology, 333 (2020), 436-448. <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/jez.2356\">Abstract<\/a><\/p>\n<p>The role of stochasticity in the origin of epigenetic variation in animal populations.<br \/>\nBiwer, C, Kawam, B, Chapelle, V, Silvestre, F. <strong>Integrative and Comparative Biology<\/strong>, 60 (2020), 1544-1557. <a href=\"https:\/\/academic.oup.com\/icb\/article-abstract\/60\/6\/1544\/5848647?redirectedFrom=fulltext\">Abstract<\/a><\/p>\n<p><strong>2019<\/strong><\/p>\n<p>Identification and expression of mangrove rivulus (Kryptolebias marmoratus) histone deacetylase (HDAC) and lysine acetyltransferase (KAT) genes.<br \/>\nFellous A, Earley RL, Silvestre F. <strong>Gene,<\/strong>\u00a0691 (2019), 56-69. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378111919300101?dgcid=coauthor#f0010\">Abstract<\/a><\/p>\n<p>Early-life exposure to the endocrine disruptor 17-\u03b1-ethinylestradiol induces delayed effects in adult brain, liver and ovotestis proteomes of a self-fertilizing fish.<br \/>\nVoisin AS, K\u00fcltz D, Silvestre F. <strong>J. Proteomics<\/strong>, 194 (2019), 112-124<em>. <\/em><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1874391918304287?via%3Dihub\">Abstract<\/a><\/p>\n<p>The Kdm\/Kmt gene families in the self-fertilizing mangrove rivulus fish, Kryptolebias marmoratus, suggest involvement of histone methylation machinery in development and reproduction.<br \/>\nFellous A, Earley RL, Silvestre F. <strong>Gene<\/strong>\u00a0687 (2019), 173-187. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0378111918311892#f0010\">Abstract<\/a><\/p>\n<p><strong>2018<\/strong><\/p>\n<p>An ecotoxicological view on neurotoxicity assessment.<br \/>\nJ. B. Legradi, C. Di Paolo, M. H. S. Kraak, H. G. van der Geest, E. L. Schymanski, A. J. Williams, M. M. L. Dingemans, R. Massei, W. Brack, X. Cousin, M.-L. Begout, R. van der Oost, A. Carion, V. Suarez-Ulloa, F. Silvestre, B. I. Escher, M. Engwall, G. Nil\u00e9n, S. H. Keiter, D. Pollet, P. Waldmann, C. Kienle, I. Werner, A.-C. Haigis, D. Knapen, L. Vergauwen, M. Spehr, W. Schulz, W. Busch, D. Leuthold, S. Scholz, C. M. vom Berg, N. Basu, C. A. Murphy, A. Lampert, J. Kuckelkorn, T. Grummt and H. Hollert. <strong>Environmental Sciences Europe<\/strong> 30:46 (2018). <a href=\"https:\/\/enveurope.springeropen.com\/articles\/10.1186\/s12302-018-0173-x\">Full text<\/a><\/p>\n<p>Behavioral effects of the neurotoxin \u00df-N-methylamino-L-alanine on the mangrove rivulus (Kryptolebias marmoratus) larvae.<br \/>\nCarion A, H\u00e9tru J, Markey A, Suarez-Ulloa V, Silvestre F. <strong>J. Xenobiotics<\/strong>.\u00a08 (2018), 7-9. <a href=\"https:\/\/pagepressjournals.org\/index.php\/xeno\/article\/view\/7820\">Full text<\/a><\/p>\n<p>DNA methylation and gene expression alterations in zebrafish early-life stages exposed to the antibacterial agent triclosan.<br \/>\nFalisse E, Ducos B, Stockwell, PA, Morison IM, Chatterjee A, Silvestre F. <strong>Env. Poll. <\/strong>. 243 (part B), 1867-1877.\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0269749118327222?via%3Dihub\">Abstract<\/a><\/p>\n<p>DNA methylation in adults and during development of the self\u2010fertilizing mangrove rivulus, Kryptolebias marmoratus.<br \/>\nFellous A, Labed-Veydert T, Locrel M, Voisin A-S, Earley RL, Silvestre F. <strong>Ecology and Evolution<\/strong>..\u00a08 (2018), 6016-6033. <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/ece3.4141\">Full text<\/a><\/p>\n<p>Physiological and proteomic responses to corticosteroid treatments in Eurasian perch, Perca fluviatilis: Investigation of immune-related parameters.<br \/>\nMilla S, Massart S, Mathieu C, Wang N, Douny C, Douxfils J, Scippo ML, De Pauw E, Dieu M, Silvestre F, Kestemont P. <strong>Comp. Biochem. Physiol. D<\/strong>.\u00a025 (2018), 86-98. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29223774\">Abstract<\/a><\/p>\n<p><strong>2017<\/strong><\/p>\n<p>Impacts of triclosan exposure on zebrafish early-life stage: toxicity and acclimation mechanisms.<br \/>\nFalisse E., Voisin A.-S.,\u00a0Silvestre F. <strong>Aquat. Toxicol.<\/strong>\u00a0189 (2017), 97-107. <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0166445X17301571\">Abstract<\/a><\/p>\n<p><strong>2016<\/strong><\/p>\n<p>DNA methyltransferases and stress-related genes expression in zebrafish larvae after exposure to heat and copper during reprogramming of DNA methylation.<br \/>\nDorts J., Falisse E., Schoofs E., Flamion E., Kestemont P., Silvestre F. <strong>Sci. Reports. <\/strong>6, 34254. <a href=\"http:\/\/www.nature.com\/articles\/srep34254\">Abstract<\/a><\/p>\n<p>Delayed impacts of developmental exposure to 17-\u03b1-ethinylestradiol in the self-fertilizing fish <em>Kryptolebias <\/em>marmoratus.<br \/>\nVoisin A.-S., Fellous A., Earley R., Silvestre F. <strong>Aquat. Toxicol.<\/strong>\u00a0180 (2016), 247-257. <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0166445X16302806\">Abstract<\/a><\/p>\n<p>Triclosan exposure results in alterations of thyroid hormone status and retarded early development and metamorphosis in Cyprinodon variegatus. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0166445X1630296X?via%3Dihub\">Abstract<\/a><br \/>\nSchnitzler JG, Fr\u00e9d\u00e9rich B, Dussenne M, Klaren PHM, Silvestre F, Das K.\u00a0 <strong>Aquat. Toxicol.<\/strong>\u00a0181 (2016),1-10.<\/p>\n<p>Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (<em>Anguilla anguilla<\/em>).<br \/>\nC. Bonnineau, D. Scaion, B. Lemaire, C. Belpaire, J-P. Thom\u00e9, M. Thonon, M. Leermaker, Y. Gao, C. Debier, F. Silvestre, P. Kestemont, J-F. Rees. <strong><span style=\"text-decoration: underline;\">Environ. Toxicol. Pharmacol.<\/span><\/strong> 45 (2016), 346-355. <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1382668916301478\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Using a novel \u201cIntegrated Biomarker Proteomic\u201d index to assess the effects of freshwater pollutants in European eel peripheral blood mononuclear cells.<br \/>\nKathleen Roland, Patrick Kestemont, Marc Dieu, Martine Raes, Fr\u00e9d\u00e9ric Silvestre. <strong><span style=\"text-decoration: underline;\">J. Proteomics<\/span>.<\/strong> 137 (2016), 83-96. <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1874391916300094\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p><strong>2014<\/strong><\/p>\n<p>Effects of cadmium exposure on the gill proteome of Cottus gobio: Modulatory effects of prior thermal acclimation.<br \/>\nDorts, J., Kestemont, P., Th\u00e9zenas, M.L., Raes, M., Silvestre, F. <strong>Aquat. Toxicol.<\/strong> 154 (2014), 87-96. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24874008\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p><strong>2013<\/strong><\/p>\n<p>Environmental OMICS: Current Status and Future Directions.<br \/>\nYue Ge, Da-Zhi Wang, Jen-Fu Chiu, Susana Cristobal, David Sheehan, Fr\u00e9d\u00e9ric Silvestre, Xianxuan Peng, Hui Li, Zhiyuan Gong, Siew Hong Lam, Hu Wentao, Hitoshi Iwahashi, Jianjun Liu, Nan Mei, Leming Shi, Maribel Bruno, Heidi Foth, Kevin Teichman. <strong>J. Integrated Omics<\/strong>. 3 (2013). <a href=\"http:\/\/www.jiomics.com\/index.php\/jio\/article\/view\/141\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Looking for protein expression signatures in European eel peripheral blood mononuclear cells after in vivo exposure to perfluorooctane sulfonate and a real world field study.<br \/>\nRoland K, Kestemont P, Loos R, Tavazzi S, Paracchini B, Belpaire C, Dieu M, Raes M, Silvestre F. <strong>Sci. Tot. Environ.<\/strong> 468-469c (2013), 959-967. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24095681\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Development of an analytical method to detect metabolites of nitrofurans. Application to the study of furazolidone elimination in Vietnamese black tiger shrimp (Penaeus monodon).<br \/>\nDouny C., Widart J., Phuong N.T., Depauw E., Silvestre F., Kestemont P., Maghuin-Rogister G. <strong>Aquaculture<\/strong>. 376-379 (2013), 54-58. <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0044848612006576\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract.<\/a><\/p>\n<p>Proteomic responses of peripheral blood mononuclear cells in the European eel (<em>Anguilla anguilla<\/em>) after perfluorooctane sulfonate exposure.<br \/>\nRoland K, Kestemont P, H\u00e9nuset L, Pierrard MA, Raes M, Dieu M, Silvestre F. <strong>Aquat. Toxicol.<\/strong> 128-129 (2013), 43-52. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23261670\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p><strong>2012<\/strong><\/p>\n<p>Physiological and proteomic responses to single and repeated hypoxia in juvenile Eurasian perch under domestication \u2013 Clues to physiological acclimation and humoral immune modulations.<br \/>\nDouxfils, J., Deprez M, Mandiki R., Milla S., Henrotte E.,\u00a0Mathieu C., Silvestre F., Vandecan N, Rougeot C., M\u00e9lard C, Dieu M, Raes M., Kestemont P. <strong>Fish Shellfish Immunol.<\/strong> 33 (2012), 1112-1122. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Physiological+and+proteomic+responses+to+single+and+repeated+hypoxia+in+juvenile+Eurasian\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Proteomics to assess the role of phenotypic plasticity in aquatic organisms exposed to pollution and global warming.<br \/>\nSilvestre, F., Gillardin, V., Dorts, J. <strong>Int. Comp. Biol.<\/strong> 52 (2012), 681-694. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22641836\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Fish peripheral blood mononuclear cell preparation for future monitoring applications.<br \/>\nPierrard MA, Roland K, Kestemont P, Silvestre F. <strong>Anal. Biochem. Meth. Biol. Sci.<\/strong> 426 (2012), 153-165. <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0003269712002217?v=s5\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Proteomic analysis of blood cells in fish exposed to chemotherapeutics: Evidence for long term effects.<br \/>\nPierrard, M-A., Kestemont, P., Phuong, N.T., Delaive, E., Thezenas, M-L., Dieu, M., Raes, M., Silvestre, F., <strong>J. Proteomics. <\/strong>75 (2012), 2454-2467<strong>.<\/strong> <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1874391912001121\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Malachite green toxicity assessed on Asian catfish primary cultures of peripheral blood mononuclear cells by a proteomic analysis.<br \/>\nM-A. Pierrard, P. Kestemont, E. Delaive, M. Dieu, M. Raes, F. Silvestre, <strong>Aquat. Toxicol.<\/strong> 114-115 (2012), 142-152. <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0166445X12000707?v=s5\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Combined analysis of <em>Perca fluviatilis<\/em> reproductive performance and oocyte proteomic profile.<br \/>\nM.-D. Castets, B. Schaerlinger, F. Silvestre, J.-N. Gardeur, C. Corbier, P. Kestemont, P. Fontaine., <strong>Theriogenology<\/strong>. 78 (2012), 432-442.<\/p>\n<p>Combined effects of deltamethrin, temperature and salinity on oxidative stress biomarkers and acetylcholinesterase activity in the black tiger shrimp (<em>Penaeus monodon<\/em>).<br \/>\nTu, H. T., Silvestre, F., Phuong, N.T., Kestemont, <strong>Chemosphere.<\/strong> 86 (2012), 83-91. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22075054\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Proteasome and antioxidant responses in <em>Cottus gobio<\/em> during a combined exposure to heat stress and cadmium.<br \/>\nDorts, J., Bauwin, A., Kestemont, P., Jolly, S., Sanchez, W., Silvestre, F. <strong>Comp. Biochem. Physiol. C.<\/strong> 155 (2012), 318-324. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22033351\">Abstract<\/a><\/p>\n<p>Evidence that elevated water temperature affects the reproductive physiology of the European bullhead <em>Cottus gobio<\/em>.<br \/>\nDorts, J., Grenouillet, G., Douxfils, J., Mandiki, R., Milla, S., Silvestre, F., Kestemont, P.,<strong>. Fish Physiol. Biochem. <\/strong>38 (2012), 389-399. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21638008\">Abstract<\/a><\/p>\n<p><strong>2011<\/strong><\/p>\n<p>Physiological and proteomic evidences that domestication process differentially modulates the immune status of juvenile Eurasian perch (Perca fluviatilis) under chronic confinement stress.<br \/>\nJessica Douxfils, C\u00e9dric Mathieu, S.N.M. Mandiki, Sylvain Milla, Emilie Henrotte, Neil Wang, Michael Vandecan, Marc Dieu, Nicolas Dauchot, Lise-Marie Pigneur, Xiang Li, Carole Rougeot, Charles M\u00e9lard, Fr\u00e9d\u00e9ric Silvestre, Karine Van Doninck, Martine Raes, Patrick Kestemont. <strong>Fish and Shellfish Immunology<\/strong>. 31 (2011), 1113-1121. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22008286\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Ecotoxicoproteomics in gills of the sentinel fish species, Cottus gobio, exposed to perfluorooctane sulfonate (PFOS).<br \/>\nDorts, J., Kestemont, P., Marchand, P.-A., D\u2019Hollander, W., Th\u00e9zenas, M.-L., Raes, M., Silvestre, F. <strong>Aquat. Toxicol.<\/strong> 103 (2011), 1-8. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21392490\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Does domestication process affect stress response in juvenile Eurasian perch Perca fluviatilis?<br \/>\nDouxfils J, Mandiki SN, Marotte G, Wang N, Silvestre F, Milla S, Henrotte E, Vandecan M, Rougeot C, M\u00e9lard C, Kestemont P.<strong> Comp. Biochem. Physiol. A. <\/strong>159 (2011), 92-99. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21300167\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Proteomic response to sublethal cadmium exposure in a sentinel fish species, Cottus gobio.<br \/>\nDorts, J., Kestemont, P., Dieu, M., Raes, M., Silvestre, F. <strong>J. Proteome Res.<\/strong>, 10 (2011), 470-478. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21070074\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p><strong>2010<\/strong><\/p>\n<p>A multi-biomarker approach to assess the impact of farming systems on black tiger shrimp (Penaeus monodon).<br \/>\nTu, H. T., Silvestre, F., Bernard A., Douny, C., Phuong, N.T., Tao, C.T., Maghuin-Rogister, G., Kestemont, P. <strong>Chemosphere<\/strong>, 81 (2010), 1204-1211. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20943254\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>A differential proteomic approach to assess the effects of chemotherapeutics and production management strategy on giant tiger shrimp Penaeus monodon.<br \/>\nSilvestre Fr\u00e9d\u00e9ric, Tu Huynh Thi, Bernard Amandine, Dorts Jennifer, Dieu Marc, Raes Martine, Phuong Nguyen Thanh , Kestemont Patrick. <strong>Comp. Biochem. Physiol. D.<\/strong>, 5 (2010), 227-233. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20655818\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>A proteomic analysis of green and white sturgeon larvae exposed to heat stress and selenium.<br \/>\nFr\u00e9d\u00e9ric Silvestre, Javier Linares-Casenavea, Serge I. Doroshov, Dietmar K\u00fcltz. <strong>Sci. Tot. Environ.<\/strong>, 408 (2010), 3176-3188. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20435339\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Differential protein expression profile in the liver of pikeperch (Sander lucioperca) larvae fed with different phospholipid levels.<br \/>\nHamza Ne\u00efla, Silvestre Fr\u00e9d\u00e9ric, Mohamed Mhetli, Ines Ben Khemis, Marc Dieu, Kestemont Patrick. <strong>Comp. Biochem. Physiol. D.<\/strong>, 5 (2010), 130-137. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20434969\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Eco-, geno- and human toxicology of bio-active nanoparticles for biomedical applications.<br \/>\nJohan Robbens, Caroline Vanparys; Ingrid Nobels; Ronny\u00a0 Blust; Karen Van Hoecke; Colin Janssen; Karel De Schamphelaere; Kathleen Roland; Gersande Blanchard; Fr\u00e9d\u00e9ric Silvestre; Virginie Gillardin; Patrick Kestemont; Roel Anthonissen; Olivier Toussaint; Christelle Saout; S\u00e9bastien Vankoningsloo; Ernesto Alfaro-Moreno; Peter Hoet; Laetitia Gonzalez; Peter Dubruel; Paul Troisfontaines. <strong>Ecotoxicology<\/strong>, 269 (2010), 170-181. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19944128\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Effects of pesticides and antibiotics on penaeid shrimp with special emphases on behavioural and biomarker responses.<br \/>\nH.T. Tu, F. Silvestre, N. T. Phuong, P. Kestemont. <strong>Environ. Toxicol. Chem.,<\/strong> 29 (2010), 929-938. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20821523\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p><strong>2009<\/strong><\/p>\n<p>Adverse effects of enrofloxacin when associated with environmental stress in Tra catfish (Pangasianodon hypophthalmus).<br \/>\nWang Neil, Nkejabega Noemie, Hien Nguyen-Ngoc, Silvestre Frederic, Huynh Thi-Tu, Phuong Nguyen-Thanh, Kestemont Patrick, Huong Do-Thi-Thanh. <strong>Chemosphere<\/strong>, 77 (2009), 1577-1584. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19836822\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Oxidative stress, protein carbonylation and heat shock proteins in the giant tiger shrimp Penaeus monodon exposed to endosulfan or deltamethrin.<br \/>\nDorts, J., Silvestre, F., Tyberghein, A.-E, Tu, H.T., Douny, C., Maghuin-Rogister, G., Phuong, N., Kestemont, P. <strong>Environ. Toxicol. Pharmacol.<\/strong>, 28 (2009), 302-310. <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1382668909001021\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Acetylcholinesterase activity as a biomarker of exposure to antibiotics and pesticides in the black tiger shrimp (Penaeus monodon).<br \/>\nTu, H. T., Silvestre, F., Scippo, M.-L., Thom\u00e9, J.-P., Phuong, N.T., Kestemont, P. <strong>Ecotox. Environ. Saf.<\/strong>, 72 (2009), 1463-1470. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19427694\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Protein expression profiling in the African clawed frog Xenopus laevis tadpoles exposed to the PolyChlorinated Biphenyls mixture Aroclor 1254.<br \/>\nV. Gillardin, F. Silvestre, M. Dieu, E. Delaive, M. Raes, J.-P. Thom\u00e9, P. Kestemont. <strong>Mol. Cell. Proteomics<\/strong>, 8 (2009), 596-611. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19011258\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Effects of water emersion stressor on stress physiology, immunity and protein expression profiles in Eurasian perch (Perca fluviatilis L.) juveniles under domestication process.<br \/>\nDouxfils J, Lambert S, Milla S, Henrotte E, Wang N, Mathieu C, Siilvestre F, Mandiki SNM, Kestemont P, Vandecan M.\u00a0 ESCPB 26th Congress. Innsbruck, Austria. September 16. <strong>Comp. Biochem. Physiol.<\/strong> A 154 (2009), Suppl. 1, P.25.<\/p>\n<p><strong>2008<\/strong><\/p>\n<p>Oxidative stress response of black tiger shrimp (Penaeus monodon) to enrofloxacin and to culture system.<br \/>\nTu, H. T., Silvestre, F., Bernard A., Douny, C., Phuong, N.T., Tao, C.T., Maghuin-Rogister, G., Kestemont, P. <strong>Aquaculture<\/strong>, 285 (2008), 244-248. <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0044848608006522\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Effects of Aroclor 1254 on oxidative stress in developing Xenopus laevis tadpoles.<br \/>\nV. Gillardin, F. Silvestre, C. Divoy, J.-P. Thom\u00e9, P. Kestemont. <strong>Ecotox. Environ. Saf.<\/strong>, 72 (2008), 546-551. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18407353\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p><strong>2007<\/strong><\/p>\n<p>Is HSP70 involved in acclimation to cadmium in the Chinese mitten crab, Eriocheir sinensis ?<br \/>\nF. Silvestre, G. Trausch, P. Devos. <strong>Bull. Environ. Contam. Toxicol.<\/strong>, 78 (2007), 432-435. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17619794\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Combined effects of herbicides on biomarkers reflecting immune-endocrine interactions in goldfish. Part I: Immune and antioxidant effects.<br \/>\nMasroor, F., Mandiki, S.N.M., Douxfils, J., Silvestre, F., Coppe, P., Kestemont, P. <strong>Aquat. Toxicol.<\/strong> 81 (2007), 159-167. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17194491\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Do Sewage Treatment Plant Discharges Substantially Impair Fish Reproduction in Polluted Rivers?<br \/>\nDouxfils Jessica, Mandiki Robert, Silvestre Frederic, Bertrand Arnaud, Leroy Delphine, Thom\u00e9 Jean-Pierre, Kestemont Patrick.<strong> Sci. Total Environ.<\/strong>, 372 (2007), 497-514. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17112566\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p><strong>2006<\/strong><\/p>\n<p>Differential protein expression profiles in anterior gills of Eriocheir sinensis during acclimation to cadmium.<br \/>\nF. Silvestre, J.-F. Dierick, V. Dumont, M. Dieu, M. Raes, P. Devos. <strong>Aquat. Toxicol.<\/strong>, 76 (2006), 46-58. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16249038\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Multiscale approach of fish responses to different types of environmental contaminations: a case study.<br \/>\nMayon N, Bertrand A, Leroy D, Malbrouck C, Mandiki SNM, Silvestre F, Goffart A, Thom\u00e9 JP, Kestemont P. <strong>Sci. Total Environ.<\/strong>, 367 (2006), 715-731. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16740295\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p><strong>Before<\/strong><\/p>\n<p>Tissue-specific cadmium accumulation and metallothionein-like protein levels during acclimation process in the Chinese crab Eriocheir sinensis.<br \/>\nF. Silvestre, C. Duch\u00eane, G. Trausch, P. Devos. <strong>Comp. Biochem. Physiol. C<\/strong>, 140 (2005), 39-45. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15792621\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Hyper-osmoregulatory capacity of the Chinese mitten crab (Eriocheir sinensis) exposed to cadmium. Acclimation during chronic exposure.<br \/>\nF. Silvestre, G. Trausch, P. Devos. <strong>Comp. Biochem. Physiol. C<\/strong>, 140 (2005), 29-37. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15792620\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Uptake of Cadmium through isolated perfused gills of the Chinese mitten crab, Eriocheir sinensis.<br \/>\nF. Silvestre, G. Trausch, A. P\u00e9queux, P. Devos. <strong>Comp. Biochem. Physiol. A<\/strong>, 137 (2004), 189-196. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14720604\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Effects of atrazine on sex stero\u00efd dynamics, plasma vitellogenin concentration and gonad development in adult Goldfish (Carassius auratus).<br \/>\nL. Span\u00f2, S.N.M. Mandiki, R. van Aerle, C.R. Tyler, F. Silvestre, P. Devos, J.-P. Thom\u00e9, P. Kestemont. <strong>Aquat. Toxicol.<\/strong>, 66 (2004), 369-379. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15168945\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<p>Effects of atrazine on osmoregulation in the Chinese mitten crab, Eriocheir sinensis. F. Silvestre, G. Trausch, L. Sp\u00e0no, P. Devos. <strong>Comp. Biochem. Physiol. C<\/strong>, 132 (2002), 385-390. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12161172\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/p>\n<div style=\"margin: 20px 0;\"><div class=\"qrcswholewtapper\" style=\"text-align:center;\"><div class=\"qrcprowrapper\"  id=\"qrcwraa2leds\"><div class=\"qrc_canvass\" id=\"qrc_cuttenpages_2\" style=\"display:inline-block\" data-text=\"https:\/\/sciences-unamur.be\/bio\/system-ecotox\/publications\/\"><\/div><div><a download=\"Publications.png\" class=\"qrcdownloads\" id=\"worign\">\r\n           <button type=\"button\" style=\"min-width:150px;background:#44d813;color:#000;font-weight: 600;border: 1px solid #44d813;border-radius:20px;font-size:12px;padding: 6px 0;\" class=\"uqr_code_btn\">Download QR<\/button>\r\n           <\/a><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Find PDF of major publications on the ResearchGate profile of Frederic Silvestre 2025 Epigenetic aging in a self-fertilizing vertebrate, the mangrove rivulus Kryptolebias marmoratus. B\u00e9lik J. and Silvestre F. bioRxiv preprint (2025). https:\/\/doi.org\/10.1101\/2025.09.19.677260. Open Access Embryonic thermal environments drive plasticity in gene expression. Anthony A. Snead, Corey R. Quackenbush, Shawn Trojahn, Anna L. McDonald, Luana&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-1669","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sciences-unamur.be\/bio\/system-ecotox\/wp-json\/wp\/v2\/pages\/1669","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sciences-unamur.be\/bio\/system-ecotox\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sciences-unamur.be\/bio\/system-ecotox\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sciences-unamur.be\/bio\/system-ecotox\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sciences-unamur.be\/bio\/system-ecotox\/wp-json\/wp\/v2\/comments?post=1669"}],"version-history":[{"count":43,"href":"https:\/\/sciences-unamur.be\/bio\/system-ecotox\/wp-json\/wp\/v2\/pages\/1669\/revisions"}],"predecessor-version":[{"id":4010,"href":"https:\/\/sciences-unamur.be\/bio\/system-ecotox\/wp-json\/wp\/v2\/pages\/1669\/revisions\/4010"}],"wp:attachment":[{"href":"https:\/\/sciences-unamur.be\/bio\/system-ecotox\/wp-json\/wp\/v2\/media?parent=1669"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}