Find PDF of major publications on the ResearchGate profile of Frederic Silvestre
2025
Water-borne cortisol levels show individuality and predict bold/shy behaviors in the self-fertilizing fish Kryptolebias marmoratus.
Mathiron G.E.A. and Silvestre F. Belgian Journal of Zoology, 155 (2025). Open Access
2024
Comparative study of the growth, stress status and reproductive capabilities of four wild-type zebrafish (Danio rerio) lines.
Chevalier C., Denis C., Nedjar S.-A., Ledoré Y., Silvestre F., Schaerlinger B. & Milla S. Biological Research, 57 (2024). Open Access
2023
Environmental Epigenomes.
Bambarendage P.U., Silvestre, F. Epigenomes, 7 (2023). Open Access
Tools for photomotor response assay standardization in ecotoxicological studies: Example of exposure to gentamicin in the freshwater planaria Schmidtea mediterranea.
Mathiron, A., Rejo, L., Chapeau, F., Malgouyres Silvestre, F., Vignet, C. Environmental Toxicology and Pharmacology, 102 (2023), 104242. Abstract
Early-life exposure to permethrin affects phenotypic traits in both larval and adult mangrove rivulus Kryptolebias marmoratus.
Mathiron, A, Gallego, G & Silvestre, F. Aquatic Toxicology, 259 (2023). Abstract
Early-life exposure to methylmercury induces reversible behavioral impairments and gene expression modifications in one isogenic lineage of mangrove rivulus fish Kryptolebias marmoratus.
Chapelle, V, Lambert, J, Deom, T, Tessier, E, Amouroux, D & Silvestre, F. Aquatic Toxicology, 258 (2023). Abstract
2022
Population Epigenetics: The Extent of DNA Methylation Variation in Wild Animal Populations.
Chapelle, V & Silvestre, F. Epigenomes, 6 (2022). doi.org/10.3390/epigenomes6040031.
Genome-wide DNA methylation of the liver reveals delayed effects of early-life exposure to 17-α-ethinylestradiol in the self-fertilizing mangrove rivulus.
Voisin, A-S, Suarez Ulloa, V, Stockwell, PA, Chatterjee, A, Silvestre, F. Epigenetics, 17 (2022), 473-497. Abstract
2020
Behavior and gene expression in the brain of adult self-fertilizing mangrove rivulus fish (Kryptolebias marmoratus) after early life exposure to the neurotoxin β-N-methylamino-L-alanine (BMAA).
Carion, A, Markey, A, Hétru, J, Carpentier, C, Suarez-Ulloa, V, Denoël, M, Earley, RL & Silvestre, F. Neurotoxicology, 79 (2020), 110-121. Abstract
Signaling pathways of oxidative stress in aquatic organisms exposed to xenobiotics.
Silvestre, F. J. Exp. Zool. Part A: Ecological and Integrative Physiology, 333 (2020), 436-448. Abstract
The role of stochasticity in the origin of epigenetic variation in animal populations.
Biwer, C, Kawam, B, Chapelle, V, Silvestre, F. Integrative and Comparative Biology, 60 (2020), 1544-1557. Abstract
2019
Identification and expression of mangrove rivulus (Kryptolebias marmoratus) histone deacetylase (HDAC) and lysine acetyltransferase (KAT) genes.
Fellous A, Earley RL, Silvestre F. Gene, 691 (2019), 56-69. Abstract
Early-life exposure to the endocrine disruptor 17-α-ethinylestradiol induces delayed effects in adult brain, liver and ovotestis proteomes of a self-fertilizing fish.
Voisin AS, Kültz D, Silvestre F. J. Proteomics, 194 (2019), 112-124. Abstract
The Kdm/Kmt gene families in the self-fertilizing mangrove rivulus fish, Kryptolebias marmoratus, suggest involvement of histone methylation machinery in development and reproduction.
Fellous A, Earley RL, Silvestre F. Gene 687 (2019), 173-187. Abstract
2018
An ecotoxicological view on neurotoxicity assessment.
J. B. Legradi, C. Di Paolo, M. H. S. Kraak, H. G. van der Geest, E. L. Schymanski, A. J. Williams, M. M. L. Dingemans, R. Massei, W. Brack, X. Cousin, M.-L. Begout, R. van der Oost, A. Carion, V. Suarez-Ulloa, F. Silvestre, B. I. Escher, M. Engwall, G. Nilén, S. H. Keiter, D. Pollet, P. Waldmann, C. Kienle, I. Werner, A.-C. Haigis, D. Knapen, L. Vergauwen, M. Spehr, W. Schulz, W. Busch, D. Leuthold, S. Scholz, C. M. vom Berg, N. Basu, C. A. Murphy, A. Lampert, J. Kuckelkorn, T. Grummt and H. Hollert. Environmental Sciences Europe 30:46 (2018). Full text
Behavioral effects of the neurotoxin ß-N-methylamino-L-alanine on the mangrove rivulus (Kryptolebias marmoratus) larvae.
Carion A, Hétru J, Markey A, Suarez-Ulloa V, Silvestre F. J. Xenobiotics. 8 (2018), 7-9. Full text
DNA methylation and gene expression alterations in zebrafish early-life stages exposed to the antibacterial agent triclosan.
Falisse E, Ducos B, Stockwell, PA, Morison IM, Chatterjee A, Silvestre F. Env. Poll. . 243 (part B), 1867-1877. Abstract
DNA methylation in adults and during development of the self‐fertilizing mangrove rivulus, Kryptolebias marmoratus.
Fellous A, Labed-Veydert T, Locrel M, Voisin A-S, Earley RL, Silvestre F. Ecology and Evolution.. 8 (2018), 6016-6033. Full text
Physiological and proteomic responses to corticosteroid treatments in Eurasian perch, Perca fluviatilis: Investigation of immune-related parameters.
Milla S, Massart S, Mathieu C, Wang N, Douny C, Douxfils J, Scippo ML, De Pauw E, Dieu M, Silvestre F, Kestemont P. Comp. Biochem. Physiol. D. 25 (2018), 86-98. Abstract
2017
Impacts of triclosan exposure on zebrafish early-life stage: toxicity and acclimation mechanisms.
Falisse E., Voisin A.-S., Silvestre F. Aquat. Toxicol. 189 (2017), 97-107. Abstract
2016
DNA methyltransferases and stress-related genes expression in zebrafish larvae after exposure to heat and copper during reprogramming of DNA methylation.
Dorts J., Falisse E., Schoofs E., Flamion E., Kestemont P., Silvestre F. Sci. Reports. 6, 34254. Abstract
Delayed impacts of developmental exposure to 17-α-ethinylestradiol in the self-fertilizing fish Kryptolebias marmoratus.
Voisin A.-S., Fellous A., Earley R., Silvestre F. Aquat. Toxicol. 180 (2016), 247-257. Abstract
Triclosan exposure results in alterations of thyroid hormone status and retarded early development and metamorphosis in Cyprinodon variegatus. Abstract
Schnitzler JG, Frédérich B, Dussenne M, Klaren PHM, Silvestre F, Das K. Aquat. Toxicol. 181 (2016),1-10.
Accumulation of neurotoxic organochlorines and trace elements in brain of female European eel (Anguilla anguilla).
C. Bonnineau, D. Scaion, B. Lemaire, C. Belpaire, J-P. Thomé, M. Thonon, M. Leermaker, Y. Gao, C. Debier, F. Silvestre, P. Kestemont, J-F. Rees. Environ. Toxicol. Pharmacol. 45 (2016), 346-355. Abstract
Using a novel “Integrated Biomarker Proteomic” index to assess the effects of freshwater pollutants in European eel peripheral blood mononuclear cells.
Kathleen Roland, Patrick Kestemont, Marc Dieu, Martine Raes, Frédéric Silvestre. J. Proteomics. 137 (2016), 83-96. Abstract
2014
Effects of cadmium exposure on the gill proteome of Cottus gobio: Modulatory effects of prior thermal acclimation.
Dorts, J., Kestemont, P., Thézenas, M.L., Raes, M., Silvestre, F. Aquat. Toxicol. 154 (2014), 87-96. Abstract
2013
Environmental OMICS: Current Status and Future Directions.
Yue Ge, Da-Zhi Wang, Jen-Fu Chiu, Susana Cristobal, David Sheehan, Frédéric Silvestre, Xianxuan Peng, Hui Li, Zhiyuan Gong, Siew Hong Lam, Hu Wentao, Hitoshi Iwahashi, Jianjun Liu, Nan Mei, Leming Shi, Maribel Bruno, Heidi Foth, Kevin Teichman. J. Integrated Omics. 3 (2013). Abstract
Looking for protein expression signatures in European eel peripheral blood mononuclear cells after in vivo exposure to perfluorooctane sulfonate and a real world field study.
Roland K, Kestemont P, Loos R, Tavazzi S, Paracchini B, Belpaire C, Dieu M, Raes M, Silvestre F. Sci. Tot. Environ. 468-469c (2013), 959-967. Abstract
Development of an analytical method to detect metabolites of nitrofurans. Application to the study of furazolidone elimination in Vietnamese black tiger shrimp (Penaeus monodon).
Douny C., Widart J., Phuong N.T., Depauw E., Silvestre F., Kestemont P., Maghuin-Rogister G. Aquaculture. 376-379 (2013), 54-58. Abstract.
Proteomic responses of peripheral blood mononuclear cells in the European eel (Anguilla anguilla) after perfluorooctane sulfonate exposure.
Roland K, Kestemont P, Hénuset L, Pierrard MA, Raes M, Dieu M, Silvestre F. Aquat. Toxicol. 128-129 (2013), 43-52. Abstract
2012
Physiological and proteomic responses to single and repeated hypoxia in juvenile Eurasian perch under domestication – Clues to physiological acclimation and humoral immune modulations.
Douxfils, J., Deprez M, Mandiki R., Milla S., Henrotte E., Mathieu C., Silvestre F., Vandecan N, Rougeot C., Mélard C, Dieu M, Raes M., Kestemont P. Fish Shellfish Immunol. 33 (2012), 1112-1122. Abstract
Proteomics to assess the role of phenotypic plasticity in aquatic organisms exposed to pollution and global warming.
Silvestre, F., Gillardin, V., Dorts, J. Int. Comp. Biol. 52 (2012), 681-694. Abstract
Fish peripheral blood mononuclear cell preparation for future monitoring applications.
Pierrard MA, Roland K, Kestemont P, Silvestre F. Anal. Biochem. Meth. Biol. Sci. 426 (2012), 153-165. Abstract
Proteomic analysis of blood cells in fish exposed to chemotherapeutics: Evidence for long term effects.
Pierrard, M-A., Kestemont, P., Phuong, N.T., Delaive, E., Thezenas, M-L., Dieu, M., Raes, M., Silvestre, F., J. Proteomics. 75 (2012), 2454-2467. Abstract
Malachite green toxicity assessed on Asian catfish primary cultures of peripheral blood mononuclear cells by a proteomic analysis.
M-A. Pierrard, P. Kestemont, E. Delaive, M. Dieu, M. Raes, F. Silvestre, Aquat. Toxicol. 114-115 (2012), 142-152. Abstract
Combined analysis of Perca fluviatilis reproductive performance and oocyte proteomic profile.
M.-D. Castets, B. Schaerlinger, F. Silvestre, J.-N. Gardeur, C. Corbier, P. Kestemont, P. Fontaine., Theriogenology. 78 (2012), 432-442.
Combined effects of deltamethrin, temperature and salinity on oxidative stress biomarkers and acetylcholinesterase activity in the black tiger shrimp (Penaeus monodon).
Tu, H. T., Silvestre, F., Phuong, N.T., Kestemont, Chemosphere. 86 (2012), 83-91. Abstract
Proteasome and antioxidant responses in Cottus gobio during a combined exposure to heat stress and cadmium.
Dorts, J., Bauwin, A., Kestemont, P., Jolly, S., Sanchez, W., Silvestre, F. Comp. Biochem. Physiol. C. 155 (2012), 318-324. Abstract
Evidence that elevated water temperature affects the reproductive physiology of the European bullhead Cottus gobio.
Dorts, J., Grenouillet, G., Douxfils, J., Mandiki, R., Milla, S., Silvestre, F., Kestemont, P.,. Fish Physiol. Biochem. 38 (2012), 389-399. Abstract
2011
Physiological and proteomic evidences that domestication process differentially modulates the immune status of juvenile Eurasian perch (Perca fluviatilis) under chronic confinement stress.
Jessica Douxfils, Cédric Mathieu, S.N.M. Mandiki, Sylvain Milla, Emilie Henrotte, Neil Wang, Michael Vandecan, Marc Dieu, Nicolas Dauchot, Lise-Marie Pigneur, Xiang Li, Carole Rougeot, Charles Mélard, Frédéric Silvestre, Karine Van Doninck, Martine Raes, Patrick Kestemont. Fish and Shellfish Immunology. 31 (2011), 1113-1121. Abstract
Ecotoxicoproteomics in gills of the sentinel fish species, Cottus gobio, exposed to perfluorooctane sulfonate (PFOS).
Dorts, J., Kestemont, P., Marchand, P.-A., D’Hollander, W., Thézenas, M.-L., Raes, M., Silvestre, F. Aquat. Toxicol. 103 (2011), 1-8. Abstract
Does domestication process affect stress response in juvenile Eurasian perch Perca fluviatilis?
Douxfils J, Mandiki SN, Marotte G, Wang N, Silvestre F, Milla S, Henrotte E, Vandecan M, Rougeot C, Mélard C, Kestemont P. Comp. Biochem. Physiol. A. 159 (2011), 92-99. Abstract
Proteomic response to sublethal cadmium exposure in a sentinel fish species, Cottus gobio.
Dorts, J., Kestemont, P., Dieu, M., Raes, M., Silvestre, F. J. Proteome Res., 10 (2011), 470-478. Abstract
2010
A multi-biomarker approach to assess the impact of farming systems on black tiger shrimp (Penaeus monodon).
Tu, H. T., Silvestre, F., Bernard A., Douny, C., Phuong, N.T., Tao, C.T., Maghuin-Rogister, G., Kestemont, P. Chemosphere, 81 (2010), 1204-1211. Abstract
A differential proteomic approach to assess the effects of chemotherapeutics and production management strategy on giant tiger shrimp Penaeus monodon.
Silvestre Frédéric, Tu Huynh Thi, Bernard Amandine, Dorts Jennifer, Dieu Marc, Raes Martine, Phuong Nguyen Thanh , Kestemont Patrick. Comp. Biochem. Physiol. D., 5 (2010), 227-233. Abstract
A proteomic analysis of green and white sturgeon larvae exposed to heat stress and selenium.
Frédéric Silvestre, Javier Linares-Casenavea, Serge I. Doroshov, Dietmar Kültz. Sci. Tot. Environ., 408 (2010), 3176-3188. Abstract
Differential protein expression profile in the liver of pikeperch (Sander lucioperca) larvae fed with different phospholipid levels.
Hamza Neïla, Silvestre Frédéric, Mohamed Mhetli, Ines Ben Khemis, Marc Dieu, Kestemont Patrick. Comp. Biochem. Physiol. D., 5 (2010), 130-137. Abstract
Eco-, geno- and human toxicology of bio-active nanoparticles for biomedical applications.
Johan Robbens, Caroline Vanparys; Ingrid Nobels; Ronny Blust; Karen Van Hoecke; Colin Janssen; Karel De Schamphelaere; Kathleen Roland; Gersande Blanchard; Frédéric Silvestre; Virginie Gillardin; Patrick Kestemont; Roel Anthonissen; Olivier Toussaint; Christelle Saout; Sébastien Vankoningsloo; Ernesto Alfaro-Moreno; Peter Hoet; Laetitia Gonzalez; Peter Dubruel; Paul Troisfontaines. Ecotoxicology, 269 (2010), 170-181. Abstract
Effects of pesticides and antibiotics on penaeid shrimp with special emphases on behavioural and biomarker responses.
H.T. Tu, F. Silvestre, N. T. Phuong, P. Kestemont. Environ. Toxicol. Chem., 29 (2010), 929-938. Abstract
2009
Adverse effects of enrofloxacin when associated with environmental stress in Tra catfish (Pangasianodon hypophthalmus).
Wang Neil, Nkejabega Noemie, Hien Nguyen-Ngoc, Silvestre Frederic, Huynh Thi-Tu, Phuong Nguyen-Thanh, Kestemont Patrick, Huong Do-Thi-Thanh. Chemosphere, 77 (2009), 1577-1584. Abstract
Oxidative stress, protein carbonylation and heat shock proteins in the giant tiger shrimp Penaeus monodon exposed to endosulfan or deltamethrin.
Dorts, J., Silvestre, F., Tyberghein, A.-E, Tu, H.T., Douny, C., Maghuin-Rogister, G., Phuong, N., Kestemont, P. Environ. Toxicol. Pharmacol., 28 (2009), 302-310. Abstract
Acetylcholinesterase activity as a biomarker of exposure to antibiotics and pesticides in the black tiger shrimp (Penaeus monodon).
Tu, H. T., Silvestre, F., Scippo, M.-L., Thomé, J.-P., Phuong, N.T., Kestemont, P. Ecotox. Environ. Saf., 72 (2009), 1463-1470. Abstract
Protein expression profiling in the African clawed frog Xenopus laevis tadpoles exposed to the PolyChlorinated Biphenyls mixture Aroclor 1254.
V. Gillardin, F. Silvestre, M. Dieu, E. Delaive, M. Raes, J.-P. Thomé, P. Kestemont. Mol. Cell. Proteomics, 8 (2009), 596-611. Abstract
Effects of water emersion stressor on stress physiology, immunity and protein expression profiles in Eurasian perch (Perca fluviatilis L.) juveniles under domestication process.
Douxfils J, Lambert S, Milla S, Henrotte E, Wang N, Mathieu C, Siilvestre F, Mandiki SNM, Kestemont P, Vandecan M. ESCPB 26th Congress. Innsbruck, Austria. September 16. Comp. Biochem. Physiol. A 154 (2009), Suppl. 1, P.25.
2008
Oxidative stress response of black tiger shrimp (Penaeus monodon) to enrofloxacin and to culture system.
Tu, H. T., Silvestre, F., Bernard A., Douny, C., Phuong, N.T., Tao, C.T., Maghuin-Rogister, G., Kestemont, P. Aquaculture, 285 (2008), 244-248. Abstract
Effects of Aroclor 1254 on oxidative stress in developing Xenopus laevis tadpoles.
V. Gillardin, F. Silvestre, C. Divoy, J.-P. Thomé, P. Kestemont. Ecotox. Environ. Saf., 72 (2008), 546-551. Abstract
2007
Is HSP70 involved in acclimation to cadmium in the Chinese mitten crab, Eriocheir sinensis ?
F. Silvestre, G. Trausch, P. Devos. Bull. Environ. Contam. Toxicol., 78 (2007), 432-435. Abstract
Combined effects of herbicides on biomarkers reflecting immune-endocrine interactions in goldfish. Part I: Immune and antioxidant effects.
Masroor, F., Mandiki, S.N.M., Douxfils, J., Silvestre, F., Coppe, P., Kestemont, P. Aquat. Toxicol. 81 (2007), 159-167. Abstract
Do Sewage Treatment Plant Discharges Substantially Impair Fish Reproduction in Polluted Rivers?
Douxfils Jessica, Mandiki Robert, Silvestre Frederic, Bertrand Arnaud, Leroy Delphine, Thomé Jean-Pierre, Kestemont Patrick. Sci. Total Environ., 372 (2007), 497-514. Abstract
2006
Differential protein expression profiles in anterior gills of Eriocheir sinensis during acclimation to cadmium.
F. Silvestre, J.-F. Dierick, V. Dumont, M. Dieu, M. Raes, P. Devos. Aquat. Toxicol., 76 (2006), 46-58. Abstract
Multiscale approach of fish responses to different types of environmental contaminations: a case study.
Mayon N, Bertrand A, Leroy D, Malbrouck C, Mandiki SNM, Silvestre F, Goffart A, Thomé JP, Kestemont P. Sci. Total Environ., 367 (2006), 715-731. Abstract
Before
Tissue-specific cadmium accumulation and metallothionein-like protein levels during acclimation process in the Chinese crab Eriocheir sinensis.
F. Silvestre, C. Duchêne, G. Trausch, P. Devos. Comp. Biochem. Physiol. C, 140 (2005), 39-45. Abstract
Hyper-osmoregulatory capacity of the Chinese mitten crab (Eriocheir sinensis) exposed to cadmium. Acclimation during chronic exposure.
F. Silvestre, G. Trausch, P. Devos. Comp. Biochem. Physiol. C, 140 (2005), 29-37. Abstract
Uptake of Cadmium through isolated perfused gills of the Chinese mitten crab, Eriocheir sinensis.
F. Silvestre, G. Trausch, A. Péqueux, P. Devos. Comp. Biochem. Physiol. A, 137 (2004), 189-196. Abstract
Effects of atrazine on sex steroïd dynamics, plasma vitellogenin concentration and gonad development in adult Goldfish (Carassius auratus).
L. Spanò, S.N.M. Mandiki, R. van Aerle, C.R. Tyler, F. Silvestre, P. Devos, J.-P. Thomé, P. Kestemont. Aquat. Toxicol., 66 (2004), 369-379. Abstract
Effects of atrazine on osmoregulation in the Chinese mitten crab, Eriocheir sinensis. F. Silvestre, G. Trausch, L. Spàno, P. Devos. Comp. Biochem. Physiol. C, 132 (2002), 385-390. Abstract