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Laboratory of Evolutionary and Adaptive Physiology – LEAP

Category: epigenetics

March 11, 2019

Environmental epigenetics workshop at Örebro, Sweden

Our laboratory massively participated to the first Environmental Epigenetics workshop that was organized at the University of Örebro in Sweden, the 21st and 22nd of February 2019. It was the opportunity for F Silvestre, A Carion, V Chapelle and A Wittorski to meet other researchers deeply involved in the environmental and evolutionary questions linked to…

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January 14, 2019January 14, 2019

Histone acetylation in the mangrove Rivulus

Third article in a row for our former post-doc Alexandre Fellous who has just published in the journal “Gene” his third article about epigenetics in our fish model, the mangrove Rivulus. He described the 27 enzymes involved in histone acetylation (KAT) and 17 in deacetylation (HDAC) as well as their dynamics during embryogenesis. This study aimed…

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December 20, 2018

New article in Daily Science about our review on neurotoxicity

You can find the link here Download QR

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December 18, 2018December 18, 2018

Valentine is our new PhD student

We’re proud to welcome Valentine Chapelle in our lab for the next 4 years. After a great MSc thesis on the mangrove rivulus heritability of personalities, Valentine successfully got a FRIA grant from FNRS. She will continue her work started during her master thesis and will evaluate the origin of epigenetic variability in natural populations…

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December 17, 2018December 17, 2018

Eco-neurotoxicity review

We’re happy to have published a review about the assessment of neurotoxicity of chemicals on wild species. This review has been published in Environmental Sciences Europe and put together 38 well-recognized scientists. It emphasizes the necessity to assess for neurotoxicity the thousands of chemicals that enter the natural environment due to human activities. Potential neurotoxicity…

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November 26, 2018December 18, 2018

New article about epigenetics in the mangrove rivulus

Our former post-doc researcher Alexandre Fellous has published the first data on histone methyltransferase (Kmt) and demethylase (Kdm) enzymes in our killifish model, the mangrove rivulus. This article has been published in the journal “Gene” and is a starting point to deeper analyze histone modifications during embryogenesis and the implication of epigenetic mechanisms in adaptation…

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October 8, 2018October 8, 2018

New article published in Environmental Pollution

A new article from Elodie Falisse’s thesis has been published in the journal Environmental Pollution. This study is the first in collaboration with Dr Aniruddha Chatterjee from the University of Ortago, New Zealand, which aimed at identifying the epigenetic effects of an exposure to a common pollutant (the antibacterial agent Triclosan) during the development of…

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May 18, 2018June 19, 2018

Arrival of the turquoise killifish

Our lab has just welcomed a new killifish species, the turquoise killifish Nothobranchius furzeri. This species lives in freshwater ponds of south east Africa and presents the particularity to be the vertebrate with the shortest lifespan. Antoine Wittorski is starting his PhD on the species from a comparative point of view in order to investigate…

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May 18, 2018June 19, 2018

New article published in Ecology and Evolution

A first article on our work on epigenetics in the mangrove rivulus has been published in the journal “Ecology and Evolution”. This article published by Alexandre Fellous depicts the DNA methylation profile of this fish, in adults and during embryogenesis. It also characterizes the main enzymes involved in this process. Altogether, our findings open the…

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May 18, 2018May 18, 2018

Anne-Sophie Voisin is PhD !

Our former PhD student Anne-Sophie Voisin has presented her thesis dissertation the 2nd of May. She was the first PhD student to work and to publish on our model fish species, the mangrove rivulus. She combined phenotypic, proteomic and epigenetic approaches to investigate the delayed effects in adults of an early life exposure to the…

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